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Transfection of complementary DNAs for the heavy and light subunits of human gamma-glutamylcysteine synthetase results in an elevation of intracellular glutathione and resistance to melphalan

In addition, upregulated expression of TXNIP (Thioredoxin Interacting Protein, TXNIP) in LSEC has a protective effect in improving ALD

Additionally, integrating traditional Chinese medicine with biologics helps establish a multidimensional and holistic immunoregulatory network

The primary goal is to determine whether aggressive lowering of glucose levels can prevent the loss of beta cell function that characterises the transition from impaired glucose tolerance to diabetes