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Anti-inflammatory activity of ginsenosides was shown by inhibition of several pathways, such as the p38/JNK/TBK1, AKT/NF-B, or p38 MAPK signaling pathways [258,259,260,261]

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However, for individuals with a cobalt allergy, this presence can pose a unique challenge, as their immune system may react adversely to the cobalt in Vitamin B12 supplements or fortified foods