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Although a specific transporter for p-tau has yet to be identified, the involvement of tau pathology in BBB dysfunction necessitates further investigation

After incubation in CD solutions, cell viability was measured, which revealed low cytotoxicity of all CDs exhibited in Table 2

Primary (monoclonal anti- hPrdx6, clone 3A10-2A11 antibody produced in mouse, WH0009588M1) and secondary (anti-mouse IgG (Fab Specific)-peroxidase antibody produced in goat, A3682) antibody procured from Sigma-Aldrich, E.coli strains: DH5 and M15[pREP4]

In vitro and in vivo experiments will be conducted to investigate how semaglutide interacts with GLP-1 receptors, influences insulin secretion, and modulates glucose homeostasis