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Alphaproteobacteria E_bin.147 with des and lig in the aerobic syringate degradation pathway, Desulfobacteria E_bin.53 with pad in the anaerobic phenylacetate degradation pathway and Desulfarculia E_bin.71 with bcr , bzd and bam in the anaerobic benzoyl-CoA degradation pathway, were specifically detected in L18 group (Fig

Jacobson A, Lam L, Rajendram M, Tamburini F, Honeycutt J, Pham T, Van Treuren W, Pruss K, Stabler SR, Lugo K, Bouley DM, Vilches-Moure JG, Smith M, Sonnenburg JL, Bhatt AS, Huang KC, Monack D (2018) A gut commensal-produced metabolite mediates colonization resistance to salmonella infection

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Additionally, protein translation is known to be tightly coupled to ATP production, and thus inhibition of ATP synthesis pathways (i.e., glycolysis and or mitochondrial oxidative phosphorylation) can provide an indirect snapshot of metabolic dependencies ( + or CD8 + activated HbKO T-lymphocytes showed any differences in mitochondrial dependence or glycolytic capacity compared to WT T-lymphocytes ( Figures 1M, N, Q, R )