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Abstract Since their discovery in the 1970s, extracellular vesicles (EVs) have garnered significant scientific attention due to their involvement in diverse pathological processes, including tumorigenesis

Pain management The consensus from multiple guidelines and systematic reviews is that calcium channel a2 ligands, serotonin and noradrenaline reuptake inhibitors (SNRIs) and tricyclic antidepressants (TCAs) have the best evidence to support their use in the treatment of diabetic neuropathic pain 185189

Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions

Moreover, our recent studies have reported that glutamatergic neurons in the medial septum (MS) of the basal forebrain encode negative-valence sensory events and drive avoidance behavior (Zhang et al., 2018a,2018b), while its GABAergic neurons, specifically those expressing somatostatin, encode positive-valence events and drive appetitive behavior (Shen et al., 2022)