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Description

The obesity paradox in cancermoving beyond BMI

Pol Merkur Lekarski 2007;22(131):369-72 [in Polish]

the metabolic features of distinct regions are likely indicative of tumor aggressiveness and treatment susceptibility ( 2 Core pathways and molecular basis of metabolic reprogramming 2.1 VHLHIF axis-driven glucose/carbon metabolism pathway reprogramming VHL gene mutation or inactivation is one of the most common molecular characteristics of ccRCC