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Preclinical and clinical study has indicated that immunotherapeutic agents (such as immune checkpoint inhibitors) reverse the immunosuppressive tumor microenvironment and enhance T cell-dependent elimination of residual tumor cells (209)

The slope of the linear regression line for the DSIP-treated group was significantly different from zero, indicating a steady and significant increase in fall latency over the 21 days of testing

reported that the microbiome associated with tissue affected by benign breast disease was associated with increased metabolism of cysteine and methionine, as well as increased glycosyltransferase activity and fatty acid biosynthesis

266 StranoS.MunarrizE.RossiM.CastagnoliL.ShaulY.SacchiA.et al (2001)