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In practice, these interdependent parameters are tuned in combination to achieve the desired in vivo behavior and provide the physical and pharmacokinetic scaffold on which more specialized functional units can be built

Fractions containing T6B-3xHA peptide were pooled and concentrated by centrifugal filtration using a concentrator pre-equilibrated with buffer A (Amicon Ultra 10-kDa cutoff, Millipore, UFC8010)