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By lowering phosphorus load, metabolic acidosis, and uremic toxin production, a low-protein diet (LPD) may improve CKD-associated symptoms and slow renal function deterioration (Kalantar-Zadeh et al., 2020

doi: 10.1016/S0070-2137(01)80007-8 15 FaulknerL.MengX.ParkB

Follicle-stimulating hormone and insulin-like growth factor I synergistically induce up-regulation of cartilage link protein (Crtl1) via activation of phosphatidylinositol-dependent kinase/Akt in rat granulosa cells

Mol Cell Proteomics 18(5):854-64 2019 PMC6495255 Pamir N, Pan C, Plubell DL, Hutchins PM, Tang C, Wimberger J, Irwin A, Vallim TQA, Heinecke JW, Lusis AJ