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As used herein the term "variant" should be taken to mean the exhibition of qualities that have a pattern that deviates from what occurs in nature

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a vector may have one or more restriction endonuclease recognition sites (e.g., type I, II or IIs) at which the sequences may be cut in a determinable fashion without loss of an essential biological function of the vector, and into which a nucleic acid fragment may be spliced or inserted in order to bring about its replication and cloning

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