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Androgenic alopecia (AGA), the most common type of hair loss, is characterized by shortened anagen phase or delayed telogen-to-anagen transition and miniaturization of HFs 4

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Interestingly, the gut metabolic module aspartate degradation I, which converts L-aspartate to oxaloacetate by aspartate aminotransferase, was elevated in SAD patients and the authors hypothesized that bacterial aspartate aminotransferase enzyme activity may represent a link between gut microbiome function and the tryptophan-kynurenine pathway, a key physiological system in psychiatric disorders (Butler et al., 2023)