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Artemisinin and its derivatives can reduce DNA damage, oxidative stress, and inflammation, inhibit cell proliferation, promote apoptosis, and regulate the cell cycle through multiple pathways, such as the TLR/NF-B, Keap1/Nrf2, and PI3K/Akt signaling pathways, thereby exerting a therapeutic effect on lung cancer and pre-lung cancer diseases

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These findings are consistent with data demonstrating that the survival rate of cocaine-poisoned dogs fell from 100% to 57% when ambient temperature was increased from 5 C to 5 C