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Cornel EB, van Haarst EP, Schaarsberg RW et al: The effect of biofeedback physical therapy in men with chronic pelvic pain syndrome type iii

For these reasons, supplemental vitamin B12 is proposed for treating neuropathy , as it may alleviate pain by increasing nerve regeneration and decreasing ectopic nerve firing (which causes neuropathic pain), as seen in a systematic review of 24 studies

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3.6.3.2 Microbial metabolites A substantial body of research highlights the role of gut microbiota and their metabolites, particularly SCFAs, in regulating metabolic, endocrine, and immune functions, with emerging evidence pointing to their involvement in neuro-immunoendocrine pathways through the MGBA (Silva et al., 2020)