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Whats often missed is the difference between synthetic B6 (like pyridoxine HCl) and the naturally occurring B6 found in real, whole foods

Factors that may trigger perioral dermatitis include the following: Drugs: steroid creams, ointments, and inhalers Fluorinated toothpaste Skincare lotions and creams, especially those containing petroleum jelly, paraffin base, and isopropyl myristate Sunscreens Makeup products Certain scented skincare products Ultraviolet (UV) light Heat Dust Wind Certain infections Oral contraceptives Hormones Vitamin B12 deficiency What are the signs of perioral dermatitis

However, other research leads us to think that the methylcobalamin form is excreted less frequently than the cyanocobalamin form, which suggests that it is retained in the bodys tissues better

For skin applications, topical or injectable formulations are more appropriate depending on the clinical target