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doi: 10.1111/j.1756-185X.2009.01375.x 37

Simultaneously, higher S-adenosylmethionine (SAM) availability supports key methylation-dependent pathways, which are crucial for epigenetic regulation and gene expression related to energy metabolism

International journal of mass spectrometry 305 , 103109, doi: 10.1016/j.ijms.2010.09.008 (2011)

The strength of evidence was evaluated using standardized GRADE criteria, considering factors such as study design, sample size, risk of bias, and the reproducibility of results (see Table 2)