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Hydration Support elimination/excretion via the kidney Sweating (movement, saunas, etc.) Support elimination/excretion via dermal routes Optimize Nutrition Focus on a whole foods diet to maximize fiber and nutrient density Judicious Use of Supplements and/or Pharmaceuticals Personalization of the therapeutic journey is key as each patients presentation and history is unique

For children with MTHFR mutations, supplementing with methylated forms of vitamins B12 and folate as well as other methylated compounds might be necessary

Kim HJ, Jeon HK, Lee JK, Sung CO, Do IG, Choi CH, Kim TJ, Kim BG, Bae DS, Lee JW