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Inhibition of mitochondrial complex I induces mitochondrial ferroptosis by regulating CoQH2 levels in cancer

The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer's disease

However, it has been observed that the c-Abl expression is downregulated in MMR deficient cells

Findings from animal models further support these observations, demonstrating that serum lactate levels are consistently elevated in monocrotaline-induced PH [57]