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Simultaneously, it downregulates genes associated with inflammation (IL-6, TNF-alpha), oxidative damage, fibrosis (TGF-beta in some contexts), and tissue destruction (certain metalloproteinases)

Do take long warm showers and keep the area clean and dry at all other times

Young ND, Nagarajan N, Lin SJ, Korhonen PK, Jex AR, Hall RS, Safavi-Hemami H, Kaewkong W, Bertrand D, Gao S, Seet Q, Wongkham S, Teh BT, Wongkham C, Intapan PM, Maleewong W, Yang X, Hu M, Wang Z, Hofmann A, Sternberg PW, Tan P, Wang J, Gasser RB

NK1R is widely expressed in the intestinal tract and is predominantly localized in the cytomembrane and cytoplasm of many cell types [74], including enteric neurons, interstitial cells of Cajal, epithelial cells, and immune cells [75, 76]