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Candida albicans has a broad spectrum of infections in the human body, ranging from superficial mucosal and skin infections (such as thrush, vaginal infection, and diaper rash) to deep systemic infections (such as lung and spleen)

Beyond MoPah1, several lipid metabolismrelated mutants exhibit defects in appressorium formation and pathogenicity 12,14

Iron plays a direct and causal role in the pathogenesis of diabetes mediated by -Cell exhaustion and insulin resistance (Simcox and McClain, 2013), even in the absence of apparent iron overload (Vari et al., 2007), thus precise control of iron levels in the body is critical for maintaining metabolic homeostasis (Wang et al., 2021)

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