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EGCG or Zn alone also exerted partial protective effects, with EGCG predominantly associated with reduced p-p38 activation and Zn mainly associated with enhanced expression of -catenin and E-cadherin, suggesting that EGCG-Zn may integrate functional features of both components

63 Proteomic analyses further suggest selective depletion of C-terminal degrons in eukaryotic proteins, supporting the existence of C-end rules that shape proteome composition

Kramer M, Quickert S, Sponholz C et al : Alternative Splicing of SMPD1 in Human Sepsis

[] Activated Parkin ubiquitinates OMM proteins, generating a phosphoubiquitin signal that recruits autophagy adaptors such as optineurin (OPTN) and calcium binding and coiled-coil domain 2 (CALCOCO2/NDP52)