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TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis

Abbreviations BMP: bone morphogenetic protein CMap: Connectivity Map COPD: chronic obstructive pulmonary disease CT: computed tomography DLCO: diffusing capacity of carbon monoxide DMEM: Dulbecco's modified Eagle's medium ECM: extracellular matrix FBS: fetal bovine serum FDR: false discovery rate FEV 1 : forced expiratory volume in 1 second FVC: forced vital capacity GOLD: Global Initiative for Chronic Obstructive Lung Disease GSEA: Gene Set Enrichment Analysis Lm: mean linear intercept PBS: phosphate-buffered saline TGF: transforming growth factor Vv: volume fraction

APX Peptide Labs does not provide dosing instructions for human or personal use this product is Research Use Only, and any concentration or amount used in a study should be determined by the researcher based on their own experimental protocol and institutional guidelines

Anyone considering this supplement should factor both of those realities into their decision: promising preclinical signal, very limited human clinical confirmation, no significant adverse effects observed in the small human studies that do exist