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The high evolutionary conservation of these pathways, including the unfolded protein response (UPR) which we found to be affected by dietary thiols in worms and human cells, suggests that the results presented here can be extrapolated to higher organisms as well

Moreover, invading bacteria generate ROS by themselves, whereas leukocytes are considered to be the essential player of seminal ROS (69)

On the contrast, upon the initial uptake of CUR/miR155@DssD-Hb NPs by 4T1 and B16F10 cells within 1 h, obvious yellow dots can be detected, arising from colocalization of Lyso-Tracker (green) and Cy5-miRNA (red)

A critical requirement is having failed at least six months of conservative care