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The study also identified disease-specific hydroxymethylation regions (DhMRs) associated with positive epigenetic regulatory factors influencing gene expression, such as axonal guidance signaling, GABA receptor signaling, and Wnt/-catenin/Sox, affecting neuronal development and function in HD pathogenesis (213)

Methylenetetrahydrofolate reductase genetic polymorphisms and esophageal squamous cell carcinoma susceptibility: a meta-analysis of case-control studies

Beam Therapeutics Announces Progress in Hematology and Genetic Disease Franchises and Outlines Key 2025 Anticipated Catalysts, Beam Therapeutics

In rodents, high levels of CDO are expressed in liver and adipose tissue, and both of these tissues also express high levels of CSD and have active taurine biosynthetic pathways (Stipanuk et al