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Consistently, blocking CD55 and in particular CD59 was found to increase in vitro CDC of MM cells induced by daratumumab [34, 35]

Additionally, NADPH plays a crucial role in the antioxidant systems involving GPX4, FSP1, and DHFR, primarily as an electron donor in reduction reactions (Doll et al., 2019

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Ajovy Type: MAB Usage: Preventative Dosage: 225mg, self-administered autoinjector pen or syringe, every month OR 675mg every three months (quarterly dosing) equivalent to three pre-filled syringes or autoinjector given in a single sitting at three different injection sites Mechanism of action: blocks the CGRP ligand Known side effects: itchiness or a rash Cost Ajovy is listed on the PBS