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Obesity is associated with a low-grade inflammation in white adipose tissue and liver, which may exacerbate insulin resistance, steatosis and diabetes

Hummel M, Bentink S, Berger H, Klapper W, Wessendorf S, Barth TFE, et al

Sustained treatment of sickle cell mice with haptoglobin increases HO-1 and H-ferritin expression and decreases iron deposition in the kidney without improvement in kidney function