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523 Analysis of gene expression in cortical astrocytes from old mice identified an increase in genes linked to an immune response with a decrease in expression of GFAP and genes related to neuroprotection and neuronal support, 524 and the prominent up-regulation of genes contributing to synapse elimination in astrocytes from aged hippocampus and cerebellum

Variability in Treatment Results PRP injections currently do not have a standardized protocol, leading to diverse treatment outcomes

Patients with prior nasal surgery may be at increased risk for vascular compromise due to altered blood supply and scarring to the area