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At this point, the reduced -SMA levels indicate that the bladder has transitioned from the compensatory phase to the decompensatory phase (Metcalfe et al., 2010

Am J Physiol Renal Physiol 292:F762F768

Even aggressive interventions fail to alleviate the condition when TNF- levels in the cerebrospinal fluid of migraine patients are elevated but normal in the blood (Rozen and Swidan, 2007)