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This condition is related to significant DNA damage and genomic instability, leading to neoplastic progression and initiation (Valavanidis et al., 2013)

9 Emerging research and potential therapeutic avenues 9.1 Clinical trials involving MSCs for IBD treatment Several clinical trials have also demonstrated the usefulness of employing MSC to treat IBD

The solution lies in developing biased inhibitors that block thrombins signaling via PARs while sparing its fibrin-generating function, or in creating non-absorbable agents that act locally within the tumor microenvironment

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