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Excessive or deficient copper levels can, however, lead to cytotoxicity and pathological alterations [7]

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doi: 10.1038/s41568-021-00375-9 6 SzkudliskiMLewiskiASewerynekEWajsE

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However, it should be noted that docking results are only approximations and need to be validated experimentally

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This indicated enhanced ferroptosis in fibroblast-like synoviocytes (FLSs) by downregulating PI3K-AKT-ERK1/2 signaling pathway and the activation of the P53 pathway which collectively contributed to reduced cell proliferation, migration, and invasion of FLSs

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