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Ecotoxicol Environ Saf 183:109467 Sagit M, Korkmaz F, Grgen SG, Kaya M, Akcadag A, Ozcan I (2014) The protective role of thymoquinone in the prevention of gentamicin ototoxicity

Glutathione and Hypothyroidism: Restoring Redox Balance In hypothyroidism - whether autoimmune (Hashimoto's) or non-autoimmune - the reduced metabolic rate paradoxically also creates oxidative stress, through different mechanisms: *Reduced mitochondrial efficiency - slower metabolism generates more electron leakage and ROS per unit of energy produced *Impaired antioxidant enzyme activity - thyroid hormones regulate the expression of antioxidant enzymes including GPx and SOD