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In humans with parkin mutations, mitochondrial complex I activity is impaired (Mftoglu et al., 2004)

R.YangL.KanemuraY.et al (2018)

Clinical Journal of Sports Medicine 30(1):1-17

PMDO cultures were resistant to oxaliplatin and expressed high levels of glutamate-cysteine ligase (GCLC) causing detoxification of oxaliplatin through glutathione synthesis