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Under normal conditions, Keap1 complex-mediated ubiquitination degrades Nrf2, and when confronted with oxidative stress, Keap1 complex activity is inhibited and the Nrf2/ARE pathway is activated

doi: 10.1016/j.it.2020.07.004 173

doi: 10.1038/s41598-021-81949-3 50 KeX.PanZ.DuH.ShenY.ShenJ

For optimal results within a research setting, please adhere to standard laboratory protocols for reconstitution using research-grade water, buffer, or appropriate solvent