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Phase I studies of Acebilustat: Biomarker response and safety in patients with cystic fibrosis

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Available from: [DOI] [PubMed] [Google Scholar] 169.Gruber K, Maywald M, Rosenkranz E, Haase H, Plumakers B, Rink L

We find that the G198A mutant exhibits significantly lower O 2 consumption activity at all [CSSH] tested, in striking contrast to the G206A mutant, which is only modestly affected (Fig