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Beyond oxidative damage, alpha-synuclein ( -syn) aggregation is a central pathological hallmark of PD, as it is the major component of Lewy bodiesabnormal deposits of proteins found in the brains of patients with PD (Paulkas et al., 2024)

We could easily incur health problems due to the reduced capacity to eliminate waste substances that accumulate in the liver

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However, the gut microbiota profiles of the antidepressant-treated rats demonstrated separation from those of CUMS rats, as assessed by the PERMANOVA test for clustering of weighted and unweighted UniFrac distances ( P 0.05)