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These comparisons emphasize that nutrition strategies need to be climate-sensitive, population- and culture-specific

2003 and Khan 2011)

Under physiological conditions, these myofibroblasts are eliminated by apoptosis when repair scars form

They concluded that the "application of a prespecified treatment escalation algorithm in dogs with recent history and treatment of 1st time CHF secondary to MMVD results in a decrease in plasma NTproBNP concentrations", and that "Use of this treatment escalation algorithm allows effective targeting of treatment for CHF in dogs against an objective criterion." What this means is that natriuretic peptides may be useful in both predicting the rapidity of the progression of MVD -- the "prognostic potential" -- and also signaling when medical treatment should be increased -- what veterinarians refer to as the "titration of therapy"