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Disruption of phosphoinositide lipid signaling is implicated in cancer, diabetes, and cardiovascular disorders

doi: 10.7150/thno.29515 64 CaoJZhangXXuPWangHWangSZhangLet al

While reported in cardiovascular patients, this adverse effect remains underrecognized in migraine therapy

The inhibitory Notch ligand Dll3 , critical in maintenance of undifferentiated neural progenitors (Zhao et al, 2009) was highly expressed in p53 tumor cells (Fig