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Statistical analyses were performed using R studio 2021.09 ( Data availability The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request

Amongst randomized patients who already lost 5% body weight during the 12-week intensive lifestyle lead-in period, subsequent treatment with ZEPBOUND resulted in a statistically significant reduction in body weight compared to placebo from randomization (Week 0) to Week 72

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