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If you eat a lot of red meat, your baseline carnitine exposure will be higher and that may affect both need and gut microbial conversion to TMAO

It is characterized by progressive biliary inflammation and fibrosis, often leading to cirrhosis, portal hypertension, and liver failure, with liver transplantation remaining the only life-prolonging treatment for advanced cases 59,60

Taking the highest IQR MR of placebo treatment (2.5) as a tentative cut-off resulted in a lower sensitivity (0.3) and specificity (0.9) compared to strategy a) at 11 h

These are typically paired with photodiode array (PDA) or mass spectrometric detection (LCMS/MS) to improve specificity