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The gene encoding the 6XHis tag TEV protease was synthesized and cloned into the pET28a (+) vector with an N-terminal tag by Bam HI and Xho I restriction enzymes

It has been shown to restore glutathione pools, improve mitochondrial function, reduce markers of inflammation and oxidative stress, and even enhance insulin sensitivity

Its important to note that semaglutide has a boxed warning from the FDA (the strongest safety warning for prescription drugs) about the risk of developing thyroid C-cell tumors, especially if you have a personal or family history of this type of cancer

10.1016/j.bbamcr.2012.06.019 8 CraigJ