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Heme oxygenase-1 prevents cardiac dysfunction in streptozotocin-diabetic mice by reducing inflammation, oxidative stress, apoptosis and enhancing autophagy

However, AMPs therapy still has shortcomings, including cause systemic and local toxicity, decreased sensitivity to salt, serum, and pH, sensitization and allergy after repeated application, confounding biological functions (e.g., angiogenesis) and high manufacturing costs ( 3.3 Phytochemicals therapy The therapies bacteriophage and antimicrobial peptides bear high production costs and display low safety performance, easily causing local or systemic toxicity

6.3 Study of key metabolic pathways and metabolic networks in skin aging Metabolomics enables the qualitative and quantitative assessments of small-molecule metabolites in dermatological disorders while also facilitating the construction of metabolic networks

LNP-mediated delivery of CRISPR RNP for wide-spread in vivo genome editing in mouse cornea