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Junctophilin-2 (JPH2) anchors L-type Ca 2+ channels (LTCCs) and RyR2 in close proximity, facilitating the efficient activation of RyR2 by Ca 2+ ions entering the cardiomyocyte through LTCCs [Figure 1] [35]

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those reviews predate Dihexa and concern the receptor system, not Dihexa itself

It can directly participate in physiological reactions within cells and is widely used in food, health products, and cosmetics