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Subcutaneous protocols achieve peak plasma levels within 24 hours and maintain therapeutic concentrations for 1216 hours, which supports once-daily dosing

Molecular Metabolic Pathways , 15(2), 145157

Some commenters expressed their concern about the burden a monthly cost-sharing responsibility will have on health center patients and recommended CMS allow a co-insurance waiver for FQHC patients who consent to using APCM services to help alleviate patient cost burdens, while another commenter urged CMS to examine any existing authority to permit health centers to waive co-pays to alleviate cost burdens to patients, whether it is done by working with OIG, incorporating flexibilities from demonstration models, or working with Congress

Sakane, T., S