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Therefore, Erastin not only directly induces necroptosis but also amplifies its occurrence through the ROS generated during ferroptosis, establishing a synergistic interaction between ferroptosis and necroptosis

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Though this method is not typically used to measure cytokine levels as compared to the more common plasma measurements, it can be an important method of measure due to the short half-life of cytokines and their localization in production, thus many studies have utilized this alternate method (Sullivan et al., 2000

It inhibits tyrosinase, the enzyme that produces melanin