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Cancer-associated fibroblasts (CAFs) are another TME component that plays significant roles in tumor growth, metastasis and cancer therapy resistance by secreting various growth factors like Hepatocyte growth factor (HGF) and Epidermal growth factor (EGF)

277 In sensitizing HCC to immunotherapy, phage therapy also shows potential

J Of Clin Invest (2019) 129:2293304

However, those with specific autoimmune conditions (particularly psoriasis or rosacea, where LL-37 is naturally overexpressed locally) should consult with their healthcare provider, as adding exogenous LL-37 could potentially exacerbate hyper-immune responses in those highly specific contexts