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Cancer Res 50(23):7537-43, 1990

Two important conclusions can be drawn based on our experiments aimed at investigating the effect of deferoxamine on plasma membrane and intrasynaptosomal mitochondria potentials

Carotenoids exhibit chemopreventive effects by suppressing the harmful effects of free radicals that regulate cancer cell proliferation, cell cycle progression, invasion, inflammation, and angiogenesis by regulating several molecular events including Akt/PI3K/mTOR, cyclin/cyclin-dependent kinase (CDK), PPAR, Wnt, VEGF, MMPs, and NF-B signaling [207]