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Probiotic administration reduces intestinal leakage by, among others, affecting intestinal immunoregulation and anti-inflammatory effects (for example, an increase in sIgA production), anti-inflammatory effects, strengthening the epithelial barrier (for example, an increase in the synthesis of mucin and short-chain fatty acids (SCFAs), and the production of bacteriocins, which limit the growth of pathogenic microorganisms (for example, defensin) [8, 133, 134]

In addition, there are also possibilities to measure the level of substances of endogenous origin in the blood

Its in these numerous steps of protein production that the epigenome exerts its influence

"Whonamedit Dictionary of Medical Eponyms"