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Many diseases, including diabetes, have been associated with damage and loss of small unmyelinated or lightly myelinated fibers of the peripheral sensory and autonomic nervous system, termed small fiber neuropathy (SFN)

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Another patient had a spuriously high MCV of 122.8 fL due to cold agglutinin disease

184 A UK community practice study reported that only 36% of patients using metformin had their vitamin B12 levels checked and had this assessment added to the yearly recall, despite the test being relatively inexpensive and adding little extra burden on patient or appointment availability