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As wound healing is essential to tissue integrity and overall health, the care and management of chronic wounds in aging populations have become a critical public health concern, annual cost of treating chronic wounds, including various ulcers, are estimated to reach up to $96 billion in the U.S

DUSP22 protein levels in T cells are inversely correlated with daily urinary protein levels in SLE patients, suggesting that DUSP22 downregulation in T cell is a non-invasive biomarker for the severity of LN [110]