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Specifically, dysregulated neuronal energy metabolism can trigger apoptotic cascades via mitochondrial membrane potential collapse or abnormal pyruvate dehydrogenase complex phosphorylation, while targeting monocarboxylate transporter MCT2-mediated lactate shuttling or mitochondrial calcium uniporter (MCU) activity has emerged as a promising therapeutic strategy for neurodegenerative disorders

Date: June 28, 2013 Event: ociety of Community Research and Action Biennial Meeting Location: Miami, FL Justin Michael Williams Factors leading to treatment entry and initial reactions to 12-Step Recovery among young adults