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10.1007/s10354-015-0344-y 425

This downregulation of pro-inflammatory mediators attenuates hepatic inflammation and may help prevent the progression from simple steatosis to NASH

6 Thioredoxin, Protein Disulfide Isomerase and, Oxidative State of ACE2 6.1 Thioredoxin System and Transcription Factor Regulation The thioredoxin system is a selenium-dependent system of enzymes that regulates intracellular ROS concentration and the regeneration of antioxidants [59]

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